The outspoken Good Morning Britain star, 55, revealed he was in talks to appear on Britain’s Got Talent after Simon Cowell broke his back in three places.
However Piers, who recently clashed with his son over coronavirus restrictions, revealed he wouldn’t return to the show if judge David, 49, remained on BGT.
Discussing any future plans to return to BGT, Piers told The Sunday Mirror: “I do have conversations with BGT every now and again, particularly after Simon had his injury.
“But I couldn’t work with Walliams. I think he is a duplicitous, treacherous, piece of work.”
Piers continued with: “He is one of those people who says one thing to your face and then sticks it to you behind your back.
“If he was sitting there I wouldn’t be interested. But if he wasn’t sitting there, who knows?”
Piers also joked he would like to be the one who sacked David, who has been on the show since 2012.